Pneumotox. 2.2.1

Pneumotox is a valuable resource developed by Philippe Camus, MD, a Professor Emeritus of Pulmonary Medicine from Dijon, France. It serves as a tool to assist in the investigation and diagnosis of respiratory and cardiac conditions that are suspected to be drug-induced or iatrogenic. It is important to note that the exact diagnosis and causality assessment ultimately rest with the users.

Patients should find it reassuring to know that incidents like these are rare and are encouraged to consult their treating doctor for further guidance if needed.

Pneumotox offers information and bibliography in a more streamlined and comprehensive manner compared to traditional database searches. However, users are advised to validate the information through double-checking.

The repository within Pneumotox compiles data from over 35,000 published bibliographic references, primarily indexed in PubMed. These references are individually reviewed and categorized by causative drugs (over 1,500) as well as by patterns of respiratory involvement (over 650), encompassing various routes of administration including inhalation and topical application.

Users can access information on Pneumotox either by drug names (International Nonproprietary Names or INN) alphabetically or by patterns grouped by families. It is essential to verify the exact composition of any suspected proprietary drug, including excipients.

Although the presence of a drug reaction in Pneumotox does not confirm the diagnosis in a patient, its absence does not exclude the possibility. Users should exercise caution as there could be unpublished reports or missed information affecting the data accuracy.

In cases involving severe respiratory conditions, thorough evaluation of the patient's exposure to drugs, substances, and chemicals is crucial. Early collection of body fluids for drug and metabolites analysis should be considered, especially in critically ill patients.

Users are encouraged to assess the likelihood of drug causality using the 'Diagnosing DIRD' prompt/button and the Naranjo scale to make informed decisions on drug continuation or withdrawal. When unsure, cross-referencing with PubMed, affiliated Safety for Medicines Department/Agencies, and drug companies' Pharmacovigilance Departments is recommended for additional insights.

For any inquiries or assistance, users can contact Pneumotox round the clock via the provided contact window.

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Pneumotox V2.2 Mobile is an application developed by Cactus Mobile, Paris. The project received support through a generous grant from ERS 2019.